本次解读的文章是:Partitioning circadian transcription by SIRT6 leads to segregated control of cellular metabolism. Cell 2014 PMID: 25083875
全文基于设计完善的基因表达芯片实验数据展开。
本次解读的文章是:Partitioning circadian transcription by SIRT6 leads to segregated control of cellular metabolism. Cell 2014 PMID: 25083875
全文基于设计完善的基因表达芯片实验数据展开。
文章 Published: 30 July 2018 :Organoid cultures recapitulate esophageal adenocarcinoma heterogeneity providing a model for clonality studies and precision therapeutics
作者成功培养了EAC(食道癌的一种)的organoid ,证明了organoid可以保留肿瘤患者的原位癌 Continue reading
于2017年发表在 Nature Communications 杂志,标题是:Phylogenetic analysis of metastatic progression in breast cancer using somatic mutations and copy number aberrations ,主要完成单位来自于比利时:
于2015年发表在 Nature Medicine杂志,标题是:Subclonal diversification of primary breast cancer revealed by multiregion sequencing 来自于:Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
对50个患者取了303个样进行测序,其中13个是WGS,剩余的290个取样只是特定基因的捕获测序。偏偏是没有WES的数据。