文章标题是：《Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity》，链接是 https://www.nature.com/articles/s41588-020-00726-6 值得细读！
这个研究数据整理的非常好，可以下载的数据真多：https://singlecell.broadinstitute.org/single_cell/study/SCP542/pan-cancer-cell-line-heterogeneity#study-download
重要的应该是下面的文件 ：
CCLE_scRNAseq_github.zip
CPM_data.txt CPM - post-QC human
Metadata.txt
UMIcount_data.txt
还有区分了各个细胞系的文件：
tSNE_Bile_Duct_Cancer.txt (tSNE Bile Duct Cancer)
tSNE_Bladder_Cancer.txt (tSNE Bladder Cancer)
tSNE_Bone_Cancer.txt (tSNE Bone Cancer)
tSNE_Brain_Cancer.txt (tSNE Brain Cancer)
tSNE_Breast_Cancer.txt (tSNE Breast Cancer)
tSNE_Colon_Colorectal_Cancer.txt (tSNE Colon Colorectal Cancer)
tSNE_Endometrial_Uterine_Cancer.txt (tSNE Endometrial Uterine Cancer)
tSNE_Esophageal_Cancer.txt (tSNE Esophageal Cancer)
tSNE_Fibroblast.txt (tSNE Fibroblast)
tSNE_Gallbladder_Cancer.txt (tSNE Gallbladder Cancer)
tSNE_Gastric_Cancer.txt (tSNE Gastric Cancer)
tSNE_Head_and_Neck_Cancer.txt (tSNE Head and Neck Cancer)
tSNE_Kidney_Cancer.txt (tSNE Kidney Cancer)
tSNE_Liver_Cancer.txt (tSNE Liver Cancer)
tSNE_Lung_Cancer.txt (tSNE Lung Cancer)
tSNE_Neuroblastoma.txt (tSNE Neuroblastoma)
tSNE_Ovarian_Cancer.txt (tSNE Ovarian Cancer)
tSNE_Pancreatic_Cancer.txt (tSNE Pancreatic Cancer)
tSNE_Prostate_Cancer.txt (tSNE Prostate Cancer)
tSNE_Sarcoma.txt (tSNE Sarcoma)
tSNE_Skin_Cancer.txt (tSNE Skin Cancer)
tSNE_Thyroid_Cancer.txt (tSNE Thyroid Cancer)
如果你对单细胞数据分析还没有基础认知，可以看基础10讲：