非常好用：

• Support mutation data with annotated protein effects
• Mutation diagram/lollipop view
• Mutation table view
• 3D structure view if available

而且pfam数据库本身也提供了这个功能：

甚至还有高手用D3.JS写了一个能实现同样需求的模块

We found ourselves in the same need, we wanted such a plot (JavaScript). Thus, I add our solution, Mutations Needle Plot. The library creates an SVG image (with D3), which then may be downloaded.

• Live examples are found at BioJS: http://registry.biojs.net/client/#/detail/muts-needle-plot
• Code is available at GitHub: https://github.com/bbglab/muts-needle-plot
• And it is also a npm-package: https://www.npmjs.com/package/muts-needle-plot

You will npm in order to be able to install & run the library.

Examples may be found in the snippets folder or also the index.html - The one displayed here below

类似的高手很多：

My colleague @SolenaLS recently asked me to write something like this: (uniprot+SVG+javascript : )http://lindenb.github.io/pages/uniprot/paintsvg.html

而且ensembl数据库也提供类似的功能

Ensemble also gives similar plot.