Universal Human Reference RNA 似乎是agilent公司的，包含了10个不同的人类细胞系！roadmap对这些样本测了RNA-seq，我以后课题可能会用得着。

列表如下：

E000	Universal_Human_Reference
E003	H1_Cell_Line
E004	H1_BMP4_Derived_Mesendoderm_Cultured_Cells
E005	H1_BMP4_Derived_Trophoblast_Cultured_Cells
E006	H1_Derived_Mesenchymal_Stem_Cells
E007	H1_Derived_Neuronal_Progenitor_Cultured_Cells
E011	hESC_Derived_CD184+_Endoderm_Cultured_Cells
E012	hESC_Derived_CD56+_Ectoderm_Cultured_Cells
E013	hESC_Derived_CD56+_Mesoderm_Cultured_Cells
E016	HUES64_Cell_Line
E024	4star
E027	Breast_Myoepithelial_Cells
E028	Breast_vHMEC
E037	CD4_Memory_Primary_Cells
E038	CD4_Naive_Primary_Cells
E047	CD8_Naive_Primary_Cells
E050	Mobilized_CD34_Primary_Cells_Female
E053	Neurosphere_Cultured_Cells_Cortex_Derived
E054	Neurosphere_Cultured_Cells_Ganglionic_Eminence_Derived
E055	Penis_Foreskin_Fibroblast_Primary_Cells_skin01
E056	Penis_Foreskin_Fibroblast_Primary_Cells_skin02
E057	Penis_Foreskin_Keratinocyte_Primary_Cells_skin02
E058	Penis_Foreskin_Keratinocyte_Primary_Cells_skin03
E059	Penis_Foreskin_Melanocyte_Primary_Cells_skin01
E061	Penis_Foreskin_Melanocyte_Primary_Cells_skin03
E062	Peripheral_Blood_Mononuclear_Primary_Cells
E065	Aorta
E066	Adult_Liver
E070	Brain_Germinal_Matrix
E071	Brain_Hippocampus_Middle
E079	Esophagus
E082	Fetal_Brain_Female
E084	Fetal_Intestine_Large
E085	Fetal_Intestine_Small
E087	Pancreatic_Islets
E094	Gastric
E095	Left_Ventricle
E096	Lung
E097	Ovary
E098	Pancreas
E100	Psoas_Muscle
E104	Right_Atrium
E105	Right_Ventricle
E106	Sigmoid_Colon
E109	Small_Intestine
E112	Thymus
E113	Spleen
E114	A549
E116	GM12878
E117	HELA
E118	HEPG2
E119	HMEC
E120	HSMM
E122	HUVEC
E123	K562
E127	NHEK
E128	NHLF

来自于：http://egg2.wustl.edu/roadmap/web_portal/processed_data.html#ChipSeq_DNaseSeq

Expression quantification

Data format: Tab-delimited matrix

• Download URL:
  http://egg2.wustl.edu/roadmap/data/byDataType/rna/expression/
• EG.name.txt:is the header file containing order and names of epigenomes (columns) in the expression matrices listed below. The EG names and the RNA seq quantification include an E000 sample representing a Universal Human Reference RNA sample (HUR). Agilent's Universal Human Reference RNA is composed of total RNA from 10 human cell lines. The reference RNA is designed to be used as a reference for expression profiling experiments. Since RNA species differ in abundance between cell lines, an ideal reference sample should represent these different RNAs. Equal quantities of DNase-treated total RNA from each cell line were pooled to make the Universal Human Reference RNA. Stratagene also supplies a QPCR Human Reference Total RNA, suitable for QRT-PCR, which has undergone further DNase treatment. Further details are available at
  http://www.genomics.agilent.com/article.jsp?pageId=1452&_requestid=2183245 and
  http://www.chem.agilent.com/library/usermanuals/public/740000.pdf
• Ensembl_v65.Gencode_v10.ENSG.gene_info: details and annotations for the ENSEMBL ids in the expression matrices
• 57epigenomes.RPKM.pc: RPKM expression matrix for protein coding genes
• 57epigenomes.N.pc: RNA-seq read counts matrix for protein coding genes
• 57epigenomes.RPKM.nc: RPKM expression matrix for non-coding RNAs
• 57epigenomes.N.nc: RNA-seq read counts matrix for non-coding RNAs
• 57epigenomes.exon.RPKM.pc: RPKM expression matrix for protein coding exons
• 57epigenomes.exon.N.pc: RNA-seq read counts matrix for protein coding exons
• 57epigenomes.RPKM.intronic.pc: RNA-seq read count matrix for intronic protein-coding RNA elements
• 57epigenomes.N.intronic.pc: RNA-seq read count matrix for intronic protein-coding RNA elements
• 57epigenomes.N.rb: RNA-seq read counts matrix for ribosomal genes
• 57epigenomes.RPKM.rb: RPKM expression matrix for ribosomal RNAs
• 57epigenomes.exn.RPKM.rb: RPKM expression matrix for ribosomal gene exons
• 57epigenomes.exn.N.rb: RNA-seq read counts matrix for ribosomal gene exons

RNA-seq signal tracks

Data format: BIGWIG

• Normalized coverage (stranded libraries have two tracks per library for + and - strand with - strand track having negative values):
  http://egg2.wustl.edu/roadmap/data/byDataType/rna/signal/normalized_bigwig/stranded/